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We have written extensively about what BPC-157 actually does and the body protective compound clinical applications, and the short version is that the strongest evidence supports tendon and ligament repair, gut-lining integrity, and reduction of NSAID-related tissue damage

PMID: 11605184

But they have limits: Orthotics support your arch but don't heal damaged tissue

While p16 ink4a and SA--Gal are widely used in aging studies, emerging evidence suggests that p21 (a cyclin-dependent kinase inhibitor) may be a more robust marker of senescence in human kidney disease, particularly in contexts of chronic injury and fibrosis (Mylonas et al., 2021)

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